Ahead of what promises mouthwatering action, Pulse Sports Uganda takes you through the key areas that could decide the encounter.
Premier League leaders Arsenal visit second-placed Manchester City at the Etihad Stadium in a potential title decider.
On 75 points, Arsenal are five clear of the Citizens, but the latter have played two games less.
Ahead of what promises mouthwatering action, Pulse Sports Uganda takes you through the key areas that could decide the encounter.
Erling Haaland vs Rob Holding
While Arsenal will have to deal with one of Europe's deadliest attacks, Rob Holding and Gabriel Magalhaes, particularly at centre-back, will have the daunting task of dealing with Erling Haaland.
The Norwegian, who has already scored against the Gunners once this season, has been monstrous for backlines this season, netting 32 goals already in the league, including 21 at the Etihad.
On the other hand, Arsenal, who will continue to be without William Saliba, have conceded 34 goals already this season, including seven in the last three games.
Bukayo Saka vs Aymeric Laporte/Sergio Gomez
In the absence of Nathan Ake, who is out of this through a hamstring injury, Pep Guardiola will have to turn to one of Sergio Gomez or Aymeric Laporte to try to stop Bukayo Saka.
Each of Gomez and Laporte has featured just eight times in the league this season, and whoever is tasked to deal with Saka will have to be at their absolute best.
Saka has arguably been Arsenal's best player this season. While he has improved his overall game and threat, the fact that he has added numbers to his game has made him almost unplayable.
The English youngster has been directly involved in 24 goals in the league, including 13 goals and 11 assists. In this tie, only Haaland, on 37 goal contributions, has more.
Kevin De Bruyne vs Martin Odegaard
Like it's been over his entire spell at Manchester City, Kevin De Bruyne continues to shine and has yet again, been among the best performers in the league.
While he has only scored five times, he has garnered 15 assists, four ahead of the next, Saka. De Bruyne never shys away from the big occasion, as he has either scored or assisted against Arsenal, Manchester United and Liverpool this season.
Odegaard, on the other side is having his most potent season ever, with 19 league contributions, 12 goals and seven assists.
While he might not be at De Bruyne's level yet, the Norwegian has led his troops exemplarily with his quality and leadership attributes.
Rodri (Rodrigo Hernandez Castante) vs Thomas Partey
The tie could get interesting with the battle between two of the best defensive and or holding midfielders around: Rodri and Partey.
Rodri and Partey can protect their respective backlines, link defence to attack and break play.
However, Rodri has, in his 29 league appearances, added two goals and six assists. Partey has featured 27 times, scoring thrice and has registered a single assist.
While the eventual outcome could go down to individual battles, as highlighted, a character in these games has the potential to be the decider. One who shows more fights frequently runs home victorious.