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Manchester United vs West Ham and Fulham vs Leeds are the only all-Premier League clashes in the round five of the FA Cup that involves nine Premier League sides.
Although some Premier League fixtures have been rescheduled, the FA Cup fifth-round ties take centre stage this midweek.
There are still nine Premier League teams among the 12 participants remaining in the competition. Of the eight matchups, two are all-Premier League encounters: Manchester United vs West Ham and Fulham vs Leeds United and only one tie involve teams outside of the Premier League, Burnley vs Fleetwood.
Manchester United vs West Ham
Manchester United are fresh off winning the League Cup and are on course to win more trophies this season; however, standing in opposition in the FA Cup is a resurgent West Ham, whom they host at Old Trafford.
The Hammers qualified for the 5th round by beating Brentford in an all-Premier League tie in the 3rd round and Derby County in the 4th round. Manchester United, on the other hand, defeated Everton and Reading on their way to this round of the competition.
The head-to-head in this tie is in favour of the Red Devils, who have won the last two FA Cup meetings against West Ham. West Ham also struggle against Manchester United at Old Trafford, where they have only won once in their last 20 attempts, losing 15 and drawing four times.
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Manchester United have also progressed from the FA Cup fifth round more than any other side, having gotten past the round 41 times. They have also not failed to go past the fifth round since a 1-0 defeat to Liverpool in the 2005/06 season.
Manchester United do not have any fresh injury concerns, with only long-term absentees unavailable for the game, and would be able to name the same side that defeated Newcastle in the FA Cup final.
The involvement of Lukasz Fabianski and Vladimir Coufal remains in doubt for The Hammers.
Fulham vs Leeds United
This is the second all-Premier League clash in the FA Cup fifth round, as Fulham host Leeds United at Craven Cottage.
Fulham qualified for this round of the competition after a five-goal thriller against Sunderland in the fourth round and a third-round victory over Hull City. In the previous two rounds of this competition, Leeds United faced and defeated Accrington Stanley and Cardiff City.
This is the first meeting between both sides in an FA Cup tie. Leeds United have struggled in this competition against Premier League opponents, having lost each other's last five FA Cup ties against first-division opponents, while Fulham were soundly beaten the last time they played in the fifth round of this competition against a Premier League side, a 3-0 defeat against Tottenham.
Fulham have already beaten Leeds United this season and would be viewed as the favourites going into this match against an unstable Leeds side.
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Fulham's talisman Aleksandar Mitrovic's involvement in this tie remains a doubt, while Leeds continue to miss Rodrigo, among others.
Bristol City vs Manchester City
Bristol City host Premier League champions Manchester City at the Ashton Gate Stadium in the FA Cup's fifth round.
The Cityzens would look to get past a Bristol City side that, although they have never met in the oldest cup competition, they have beaten in an EFL Cup clash.
Manchester City have been dominant in the FA Cup against sides in the lower divisions, having won their last 12 such games. They have also won their last ten away games in this FA Cup, which is the longest away winning run in the history of the competition.
Bristol City, on the other hand, have been eliminated in 13 of their last 14 FA Cup ties, with their last win in this round of the competition coming as far back as the 1973/74 season when they defeated Leeds in a replay.
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Kevin de Bruyne and Aymeric Laporte's participation in the match is still in doubt, and John Stones has yet to return from injury. Nigel Pearson, on the other hand, who has waxed lyrical about Manchester City's Riyad Mahrez, whom he signed at Leicester, will be without at least four of his players.
The full gameweek fixtures
Stoke City vs Brighton & Hove Albion
Leicester City vs Blackburn Rovers
Fulham vs Leeds United
Bristol City vs Manchester City
Southampton vs Grimsby Town
Burnley vs Fleetwood Town
Manchester United vs West Ham
Sheffield United vs Tottenham Hotspur
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